Diaphragmatic Hernia – An abnormal opening in the diaphragm through which abdominal organs move into the thorax.Hydronephrosis – Inability of kidneys to drain urine resulting in swelling of the kidney.Omphalocele – A defect where the baby’s abdominal organs are outside the body due to a hole in the belly.Rocker bottom feet – feet shape resembling that of a rocking chair.Strawberry shaped skull can be seen in 2 nd trimester.Clenched hands with overlapping index fingers.Polyhydramnios, intra-uterine growth retardation and abnormal hand posture are suggestive of trisomy 18 during 3 rd trimester. About 3 out of 10000 live-births have trisomy 18.īabies with this trisomy generally die in the uterus itself due to multiple structural abnormalities. Nearly half of the fetuses have cardiac abnormalities and about19% have renal abnormalities.Pleural effusion, ascites and generalized edema.In 2 nd trimester fetuses have severe lymphatic abnormalities. Most fetuses suffer a spontaneous abortion.
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